Peptide Database

Peptide NameTaipehensin-1TP1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC118H170N28O35

DescriptionStandard

        TLIWEFYHQILDEYNKENKG
    

Molecular Weight2540.78 Da

Isoelectric Point (pI)4.83

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.76

Charge Density (pH 7.0) -0.1255

GRAVY Index-1.03

Hydrophobic Moment 0.55

Boman Index-0.06

Instability Index61.04

Aliphatic Index 78.00

Aromaticity 0.2000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1051.89

LogP -6.02

H-bond Donors 35.0

H-bond Acceptors 34.0

Rotatable Bonds 84.0

Heavy Atoms 181.0

Ring Count 6.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008825 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana taipehensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antioxidant Free-radical scavenging Antimicrobial activity not detected

TargetEscherichia coli ATCC 25922

ActivityNo antimicrobial activity detected

MethodAntimicrobial screening assay

RECORD: Rec_0027637 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana taipehensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antioxidant Free-radical scavenging Antimicrobial activity not detected

TargetPseudomonas aeruginosa CGMCC 1.50

ActivityNo antimicrobial activity detected

MethodAntimicrobial screening assay

RECORD: Rec_0115621 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana taipehensis [Animal]

FamilyTaipehensin

Structure & Mods

Configribosomal mature linear peptide [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Bio-Activity Profile

Function

Antioxidant Free-radical scavenging

TargetABTS and DPPH free radicals

MethodABTS/DPPH radical-scavenging assays

PaperIdentification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. Biochimie. 2014. DOI:10.1016/j.biochi.2014.07.013 PMID25066917 Evidence URLhttps://www.uniprot.org/uniprotkb/E7EKG6/entry

RECORD: Rec_0147369 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana taipehensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antioxidant Free-radical scavenging Antimicrobial activity not detected

TargetCandida albicans ATCC 10231

ActivityNo antimicrobial activity detected

MethodAntimicrobial screening assay

RECORD: Rec_0180491 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana taipehensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antioxidant Free-radical scavenging Antimicrobial activity not detected

TargetPsychrobacter faecalis X29

ActivityNo antimicrobial activity detected

MethodAntimicrobial screening assay

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