Peptide Database

Peptide Namecycloviolacin Y4

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC124H197N31O40S5

DescriptionStandard

        GVPGESCVFIPCLTGVLGCSCSSNVCYLN
    

Molecular Weight2922.40 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.57

Charge Density (pH 7.0) -0.0444

GRAVY Index0.95

Hydrophobic Moment 0.26

Boman Index0.37

Instability Index46.98

Aliphatic Index 93.79

Aromaticity 0.0690

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1105.40

LogP -13.88

H-bond Donors 42.0

H-bond Acceptors 44.0

Rotatable Bonds 88.0

Heavy Atoms 200.0

Ring Count 4.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109614 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetTrichostrongylus colubriformis

Activity2.27

MethodIC50

RECORD: Rec_0160337 VERIFIED: YES