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MYP_149007
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Basic Information
L-RW (De novo synthesis)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C83H115N29O17
Standard
Sequence
RWTWRGSGRWTWR
Physicochemical Analysis
1790.99 Da
12.00
3.76
3.56
0.2892
-1.89
0.58
-0.48
44.58
0.00
0.3077
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
783.97
-5.82
33.0
21.0
52.0
129.0
8.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037072 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PMID25683050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25683050/
RECORD: Rec_0048113 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit erythrocytes
500 μg/mL
Hemolysis
PMID29193517;25683050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29193517/
RECORD: Rec_0078285 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human bronchial epithelial cells BEAS-2B (25% Inhibition at 80 microg/ml
500 μg/mL
Hemolysis
PMID29193517;25683050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29193517/
RECORD: Rec_0087097 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Corynebacterium glutamicum ATCC 13032
0.9-0.7 μM
MIC
PMID29193517;25683050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29193517/
RECORD: Rec_0101888 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Corynebacterium glutamicum ATCC 13032
0.05 μM
IC50
PMID29193517;25683050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29193517/
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