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MYP_148993
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Basic Information
Mastoparan-C [A5,8K]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C78H148N20O16
Standard
Sequence
LNLKKLLKVAKKIL
Physicochemical Analysis
1622.13 Da
10.60
4.76
4.54
0.3397
0.46
0.83
0.01
-7.28
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
614.81
-0.83
21.0
21.0
62.0
114.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0209547 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 700603
8 μM
MIC
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0212330 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 9027
4 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0215211 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Salmonella enterica ATCC 13076
32 μM
MIC
PaperReducing Self-Assembly by Increasing Net Charge: Effect on Biological Activity of Mastoparan C.
RECORD: Rec_0229560 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus ATCC 25923
32 μM
MIC
PaperReducing Self-Assembly by Increasing Net Charge: Effect on Biological Activity of Mastoparan C.
RECORD: Rec_0259059 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
8 μM
MIC
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
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