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MYP_148991
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Basic Information
vif 101-115
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Vif multimerization inhibitor
Standard
15 amino acids
C89H122N18O25S
Standard
Sequence
DLADQLIHLYYFDCF
Physicochemical Analysis
1876.09 Da
4.05
-3.16
-3.43
-0.2108
0.40
0.45
0.29
28.35
110.67
0.2667
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
694.85
-1.64
24.0
24.0
57.0
133.0
5.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0083222 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Replication inhibition
HIV-1
Mammalian: 1.1 h; Yeast: 3 min; E. coli: >10 h
PaperPotent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. | Yang B, Gao L, Li L, Lu Z, Fan X, Patel CA, Pomerantz RJ, DuBois GC, Zhang H. | J Biol Chem. 2003 Feb 21;278(8):6596-602. | DOI:10.1074/jbc.M210164200 | PMID:12480936 PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0122045 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0133298 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:inhibit vif-vif binding
PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0279296 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 26.7%, E 0.0%, T 40.0%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
RECORD: Rec_0382808 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Vif multimerization inhibitor
H9
34 %
Inhibition
PaperPotent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/