Peptide Database

Peptide NameDefensin alpha 5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC423H679N129O138S9

DescriptionStandard

        MRTLAILAAILLVALQAQAESLQTAADEAVTQYPSEEDHKDVTVSFAGNGLSAFMASGSRARAVCYCRSGCCDYPESHTGRCTQGGRSYRLCCR
    

Molecular Weight10068.28 Da

Isoelectric Point (pI)6.69

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0041

GRAVY Index-0.09

Hydrophobic Moment 0.66

Boman Index-0.01

Instability Index49.25

Aliphatic Index 71.81

Aromaticity 0.0638

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4309.23

LogP -54.96

H-bond Donors 161.0

H-bond Acceptors 149.0

Rotatable Bonds 330.0

Heavy Atoms 699.0

Ring Count 10.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0088321 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID39432

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic

RECORD: Rec_0225083 VERIFIED: NO