Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC172H263N49O55S2

DescriptionStandard

        KCNTATCAIQRLANFLIHFSNSFGDASSPTNVGPNTY
    

Molecular Weight3961.35 Da

Isoelectric Point (pI)8.05

Net Charge (pH 7.0)0.83

Net Charge (pH 7.4) 0.54

Charge Density (pH 7.0) 0.0223

GRAVY Index-0.16

Hydrophobic Moment 0.65

Boman Index0.08

Instability Index12.34

Aliphatic Index 60.81

Aromaticity 0.1081

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1687.85

LogP -23.45

H-bond Donors 59.0

H-bond Acceptors 59.0

Rotatable Bonds 123.0

Heavy Atoms 278.0

Ring Count 7.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234183 VERIFIED: YES

Provenance & Taxonomy

OrganismCondylura cristata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)