Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length701 amino acids

Chemical FormulaC3289H5129N889O1028S16

DescriptionStandard

        MSTVLYIHPPHGCYVFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYNHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDPTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKAEAKAKAEREALFARAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPSPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPIYVILSSPYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGESPENVVMIDRLEKILKGELQPTDTDKRFYTHEVRELERYRALGIADGTVPENDYEVWNNTHTATLEDYKLSSDETLLYTPEALNSQN
    

Molecular Weight74085.29 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-30.10

Net Charge (pH 7.4) -31.27

Charge Density (pH 7.0) -0.0429

GRAVY Index-0.23

Hydrophobic Moment 0.77

Boman Index0.09

Instability Index36.29

Aliphatic Index 79.50

Aromaticity 0.0670

Extinction Coeff. Reduced 76780.00

Extinction Coeff. Oxidized 76905.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223203 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli