Peptide Database

Peptide NameSLAY-screened peptide P909

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC107H174N40O27S

DescriptionStandard

        RARSTPHNPRNIFRRKFDCL
    

Molecular Weight2484.84 Da

Isoelectric Point (pI)11.83

Net Charge (pH 7.0)4.84

Net Charge (pH 7.4) 4.57

Charge Density (pH 7.0) 0.2419

GRAVY Index-1.33

Hydrophobic Moment 0.61

Boman Index-0.56

Instability Index110.68

Aliphatic Index 44.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1126.78

LogP -12.84

H-bond Donors 42.0

H-bond Acceptors 34.0

Rotatable Bonds 80.0

Heavy Atoms 175.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222508 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/