Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC300H473N77O82S7

DescriptionStandard

        MRTFLFLFVVLFFLTPAKNAFFDEKCDKLRGTCKNSCEKNEELTSFCQKSLKCCRTI
    

Molecular Weight6694.89 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)3.45

Net Charge (pH 7.4) 3.13

Charge Density (pH 7.0) 0.0605

GRAVY Index-0.02

Hydrophobic Moment 0.54

Boman Index-0.04

Instability Index25.64

Aliphatic Index 68.42

Aromaticity 0.1404

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2609.97

LogP -22.45

H-bond Donors 97.0

H-bond Acceptors 93.0

Rotatable Bonds 228.0

Heavy Atoms 466.0

Ring Count 9.0

Amide Bonds 60.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0047093 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence