Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length661 amino acids

Chemical FormulaC3144H5013N933O983S7

DescriptionStandard

        MADDQEKHIYVKYWTVPDLGSADRAAAEATANKANGGGNSGWSIGVGGSGSGPITTGLGPGRGRRRGITNKQLKRLIRRQAAEARATAERHAAEHAAHQLRLQAEAHAQAMAEAAERSRIEAQVRAQAEKDQAHRQALETLTATYPSLHSGLAQSYLLASASLQNTIREEMVLGSDQNIDPPSDRHLLDLILHKKVRINYLLASKQSLLEERRVQTLQLTGQELDHATPKDYLNYLVRYSQGDPPRVHQAHEAWLSTLSQTCEAKLLAESITLLNEQSAALSIRYAELSLANKTASQDAERTSSRQAAGIEKLWSVIAPAATTSTASSIRTVATNIAKDQLIRIATRTLGSNLVTLLAMYPQPLGDAELPPAVVATPLSQLNLPPHIDLEYVASVKGTLDVPHRLVSNQAETSGAVSWVDADGVNVGTKVRVRTFTYNAENNSYEFIRDGESTPALIWTPIARPADSSTRSPAGPPVLPADPGNPVTPFVPELEAYPAVDRDDPDDYILISPIDSGLPNTYLLFKDPRSIPGVASGYGEAVNGVWLGDKTRAEGASIPAHIADQLRGRRFGNFDSLRKATWIAVANDPELGKQFTQHNLEIMRDGGAPYPRLSDQAGGRTKFEIHHKDHISNGGAVYDIDNLVIMTPRQHIDHHRSPKNDL
    

Molecular Weight71834.55 Da

Isoelectric Point (pI)6.35

Net Charge (pH 7.0)-5.49

Net Charge (pH 7.4) -6.98

Charge Density (pH 7.0) -0.0083

GRAVY Index-0.44

Hydrophobic Moment 0.88

Boman Index-0.04

Instability Index45.03

Aliphatic Index 86.32

Aromaticity 0.0530

Extinction Coeff. Reduced 72310.00

Extinction Coeff. Oxidized 72310.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131532 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas syringae pv. maculicola str. ES4326 [Bacterium]

FamilyPyocin/Colicin

Tax ID629265

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal