Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC49H75N9O9

DescriptionStandard

        PWVPLIPI
    

Molecular Weight934.17 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0052

GRAVY Index1.41

Hydrophobic Moment 0.16

Boman Index0.76

Instability Index15.01

Aliphatic Index 182.50

Aromaticity 0.1250

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 251.24

LogP 2.75

H-bond Donors 8.0

H-bond Acceptors 9.0

Rotatable Bonds 22.0

Heavy Atoms 67.0

Ring Count 5.0

Amide Bonds 7.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0002871 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0092671 VERIFIED: YES

Provenance & Taxonomy

OrganismPhakellia fusca [Animal]

FamilyPhakellistatin

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetTumor cells: P388 (Not active up to 100 μg/ml)

RECORD: Rec_0228149 VERIFIED: YES

Provenance & Taxonomy

OrganismPhakellia fusca [Animal]

FamilyPhakellistatin

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0267693 VERIFIED: YES

Provenance & Taxonomy

OrganismPhakellia fusca [Animal]

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Cytotoxic Anticancer

TargetHuman hepatoma BEL-7404 cell line, BEL-7404 cell line

Activity0.01 μg/mL

MethodED50

RECORD: Rec_0400855 VERIFIED: YES

Provenance & Taxonomy

OrganismPhakellia fusca [Animal]

FamilyPhakellistatin

Structure & Mods

Configside-chain cyclized/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic