Peptide Database

Peptide NameKiller protein of pyocin s3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length553 amino acids

Chemical FormulaC2715H4229N757O817S21

DescriptionStandard

        MAIGYFLLVGDKTTCGGQIITGDHTMTFNGRATAREGDKVTCGKHPGTYVIVGGVSDVFDMGRKLAGTLDSVSTCPCRARFINSEMDSYEKQDKTADRVAAPTNMAQQHFSSPVKDVGSPPATQVPPPPIPVFTKSCQRGKGCTDAGTEPESANNFGRMAIYQVPSSPAPATAQKPEPPPQDKKHPPEPGKPRDKKLPWYKRWFRSGKDNAEAAATAVAATARSAVAEGETLVMRYIGGGAISAGRWLAAPNPVTVGLMGLFYSPSLNQGEEDYLDPYRLRQIAEQYGKAPTRVRFRWIRDEKSGRMTVQGYHVSPESGLDKVPVRMMTLNRTTGNYEFWEPGETRPTILWTPNEQEFKAPAHTGNEEQPFIPSQITVLPIPDKVGSDIESLPMPEEKDFRDYILVFPIPNMPPVYVYLSKPPVKLFEVDLYRNFAGRPRNGTHADHMPSAAAVKAYFRRLYSLFDEGEFKELSDDVASIIIPAEVHQKLSATYGGRNTPTQIEQDSKDLRSALDRDFNTIKPALKEYGATEAQLEDARTKMHKLNQERGLYK
    

Molecular Weight61219.57 Da

Isoelectric Point (pI)8.04

Net Charge (pH 7.0)2.39

Net Charge (pH 7.4) 1.42

Charge Density (pH 7.0) 0.0043

GRAVY Index-0.59

Hydrophobic Moment 0.77

Boman Index-0.06

Instability Index46.23

Aliphatic Index 64.07

Aromaticity 0.0868

Extinction Coeff. Reduced 64290.00

Extinction Coeff. Oxidized 64665.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294230 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus laumondii subsp. clarkei [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperWhole-genome-based revisit of Photorhabdus phylogeny: proposal for the elevation of most Photorhabdus subspecies to the species level and description of one novel species Photorhabdus bodei sp. nov., and one novel subspecies Photorhabdus laumondii subsp. clarkei subsp. nov. PMID29877789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29877789/