MYP_148727
Basic Information
Psysol 2
Enzyme modulation Enzyme inhibition Prolyl oligopeptidase inhibitory
Other / Curated residual function label Generic enzyme inhibition annotation
Standard
29 amino acids
C118H189N35O40S6
Standard
Sequence
GLPICGESCVGGTCNTPGCTCTWPVCTRN
Physicochemical Analysis
2930.36 Da
5.96
-0.30
-0.59
-0.0102
0.16
0.26
0.16
63.89
46.90
0.0345
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1174.30
-17.87
46.0
46.0
85.0
199.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073874 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0178773 VERIFIED: YES
Provenance & Taxonomy
Psychotria solitudinum [Plant]
Cyclotide
Structure & Mods
backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
human prolyl oligopeptidase
25 μM
IC50
RECORD: Rec_0267248 VERIFIED: YES
Provenance & Taxonomy
Psychotria solitudinum [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Enzymatic-degradation Enzyme-inhibitory Prolyl oligopeptidase inhibitory
Human prolyl oligopeptidase
RECORD: Rec_0303068 VERIFIED: YES
Provenance & Taxonomy
Psychotria solitudinum [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic cyclotide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Prolyl oligopeptidase inhibitory
Human prolyl oligopeptidase
25 μM
IC50