Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 2.8

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC180H297N53O52S7

DescriptionStandard

        TVINVKCTSPKQCLKPCKDLYGPHAGAKCMNGKCKCYNN
    

Molecular Weight4260.06 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)5.42

Net Charge (pH 7.4) 5.08

Charge Density (pH 7.0) 0.1389

GRAVY Index-0.55

Hydrophobic Moment 0.57

Boman Index-0.11

Instability Index29.63

Aliphatic Index 50.00

Aromaticity 0.0513

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1707.47

LogP -20.18

H-bond Donors 62.0

H-bond Acceptors 66.0

Rotatable Bonds 141.0

Heavy Atoms 292.0

Ring Count 6.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059783 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides elegans [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-29; 13-34; 17-36

Bio-Activity Profile

Function

Toxin

TargetKv1