Peptide Database

Peptide NameDefensin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC420H668N128O117S9

DescriptionStandard

        MKFFAVFAVIFVAVCCLAAQAKASPAEERNFVHGADALKQLEPELHGRYKRATCDLLSGTGVGHSACAAHCLLRGNRGGYCNGKAVCVCRN
    

Molecular Weight9671.17 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.78

Net Charge (pH 7.4) 4.22

Charge Density (pH 7.0) 0.0525

GRAVY Index0.19

Hydrophobic Moment 0.55

Boman Index0.08

Instability Index29.55

Aliphatic Index 80.55

Aromaticity 0.0769

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3904.91

LogP -41.74

H-bond Donors 144.0

H-bond Acceptors 135.0

Rotatable Bonds 317.0

Heavy Atoms 674.0

Ring Count 13.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281707 VERIFIED: NO

Provenance & Taxonomy

OrganismMusca domestica [Animal]

FamilyDefensin

Tax ID7370

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal