Peptide Database

Peptide NameLK [L5,12C], LK-2

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC83H158N22O17S2

DescriptionStandard

        LKKLCKLLKKLCKLAG
    

Molecular Weight1800.41 Da

Isoelectric Point (pI)10.05

Net Charge (pH 7.0)5.73

Net Charge (pH 7.4) 5.49

Charge Density (pH 7.0) 0.3584

GRAVY Index0.36

Hydrophobic Moment 0.83

Boman Index-0.06

Instability Index-22.46

Aliphatic Index 152.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 655.94

LogP -1.77

H-bond Donors 25.0

H-bond Acceptors 25.0

Rotatable Bonds 69.0

Heavy Atoms 124.0

Ring Count 0.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419092 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetHIV-1 93BR020[IC90 I = 6.60+-1.60 microM]

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