Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1009H1600N266O267S9

DescriptionStandard

        PVPLPMAHEPMLLLAVTEFVANSAAFTYFTAGALRRSISSDMLPQKFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARRQPLLSFHPDALHGTLFSSAEALVVLPNATRVPAFLLNIDANVTGKPTITRNRLAGTVRLTGLVPNPELALPAPQTLLPALCWAQTLPVPQVKPLETLLKFGLWLFGVPRANSKCCPCPVP
    

Molecular Weight22017.70 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)5.29

Net Charge (pH 7.4) 4.94

Charge Density (pH 7.0) 0.0264

GRAVY Index0.15

Hydrophobic Moment 0.56

Boman Index0.14

Instability Index56.24

Aliphatic Index 100.50

Aromaticity 0.0750

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8282.61

LogP -101.58

H-bond Donors 280.0

H-bond Acceptors 285.0

Rotatable Bonds 682.0

Heavy Atoms 1551.0

Ring Count 48.0

Amide Bonds 215.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0260706 VERIFIED: NO

Provenance & Taxonomy

OrganismChaetorhynchus papuensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria