Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC454H715N131O138S14

DescriptionStandard

        YPNVDLSNMGCEECTLKKNNVFSRDRPIYQCMGCCFSRAFPTPLKAMKTMTIPKNITSEATCCVAKHSYETEVAGIRVRNHTDCHCSTCYFHKS
    

Molecular Weight10665.24 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)4.02

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.0427

GRAVY Index-0.41

Hydrophobic Moment 0.62

Boman Index-0.08

Instability Index41.62

Aliphatic Index 49.79

Aromaticity 0.0851

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4336.66

LogP -50.59

H-bond Donors 161.0

H-bond Acceptors 160.0

Rotatable Bonds 347.0

Heavy Atoms 737.0

Ring Count 17.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419150 VERIFIED: YES

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

FamilyGlycoprotein hormones

Tax ID8241

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-34; 14-63; 31-84; 35-86; 62-89

Other Mods55:N-linked (GlcNAc...) asparagine; 80:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min