Peptide Database

Peptide NameCecropin-B modified, CecM

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC190H341N55O40S2

DescriptionStandard

        KWKVLKKKIMKMLRNRINGLVKAGPALKVKLQALAL
    

Molecular Weight4100.21 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)10.75

Net Charge (pH 7.4) 10.53

Charge Density (pH 7.0) 0.2986

GRAVY Index0.04

Hydrophobic Moment 0.72

Boman Index-0.05

Instability Index22.04

Aliphatic Index 132.78

Aromaticity 0.0278

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1576.07

LogP -7.47

H-bond Donors 55.0

H-bond Acceptors 53.0

Rotatable Bonds 150.0

Heavy Atoms 287.0

Ring Count 3.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416026 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes

Activity250 μM

MethodHemolysis

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