Peptide Database

Peptide NameAntimicrobial peptide HsAp4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC375H643N115O104S4

DescriptionStandard

        MSRRRILILVLVTMLVKTMAGMESKWVETTYEIKKRSGTSEKERESGRLLGVVKRLIVGFRSPFRGRRAISEQT
    

Molecular Weight8555.09 Da

Isoelectric Point (pI)11.41

Net Charge (pH 7.0)9.51

Net Charge (pH 7.4) 9.27

Charge Density (pH 7.0) 0.1286

GRAVY Index-0.29

Hydrophobic Moment 0.70

Boman Index-0.17

Instability Index83.51

Aliphatic Index 93.38

Aromaticity 0.0541

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3619.05

LogP -34.34

H-bond Donors 136.0

H-bond Acceptors 118.0

Rotatable Bonds 302.0

Heavy Atoms 598.0

Ring Count 6.0

Amide Bonds 74.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0056289 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria