Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2426H3861N627O685S16

DescriptionStandard

        MARGPDDTWRWATLVVLAALGTAVTATTSPGVVARITQKGLDYACQQGVATLQKELEKVTIPTFSGSFKMKYLGKGKYSFYSLVIREFKLPNSQIRPLPDQDLDLSIKDASIKMSGKWKARKNFIKVSGNFDLSVDGISILAGLKLGYDPTSGHPTVTCSRCSSHVNGVRVRISRSSLGWLIQLFRKNIESSLRNSMNRKICEVVTSTVSSKLQPYFQTLPVTTKIDNVAGIDYSLVAPPKATADNLDVLLKGEFFRLAHRRPPPFAPPALTLPNDHNRMVYLGISEYLFNTAGLVYQEAGVLNFTLSDDTLPKESKFLLTTKSFGTLLPQVAKMFPDMKMQLLIWASSPPNIAMCPTGLDLTFALDTQAVAVLPDSSLAPLFLLEMYVNVSADIGARSDRLVGELKLNKLLLELKHSDIGPFPVELLQTVMNYVVPTVVIPKINEKLQKGFPLPLPASIQLFNLVFQPHQDFLLFGADVQYS
    

Molecular Weight53284.44 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)11.00

Net Charge (pH 7.4) 10.30

Charge Density (pH 7.0) 0.0228

GRAVY Index0.05

Hydrophobic Moment 0.66

Boman Index0.11

Instability Index36.60

Aliphatic Index 100.50

Aromaticity 0.0870

Extinction Coeff. Reduced 46870.00

Extinction Coeff. Oxidized 47120.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401135 VERIFIED: NO

Provenance & Taxonomy

OrganismTursiops truncatus (Atlantic bottle-nosed dolphin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria