Peptide Database

Peptide NameSyn-safencin-73

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC138H225N41O34

DescriptionStandard

        AGKETIRQYLKNEIKKKGRKAVWAW
    

Molecular Weight3002.52 Da

Isoelectric Point (pI)10.38

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.2318

GRAVY Index-1.14

Hydrophobic Moment 0.65

Boman Index-0.30

Instability Index2.40

Aliphatic Index 70.40

Aromaticity 0.1200

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1274.46

LogP -8.90

H-bond Donors 46.0

H-bond Acceptors 40.0

Rotatable Bonds 106.0

Heavy Atoms 213.0

Ring Count 5.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162569 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity>20 μM

MethodCC50

RECORD: Rec_0322052 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity0.35 μM

MethodIC50