Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length201 amino acids

Chemical FormulaC1036H1553N225O309S8

DescriptionStandard

        IDDLAEVDYSLSSLPAVFQPFIDLDLKGTVYTAGNYTDPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSLAYYIAGAFNTTITEEVKSGKLLSFFFFFSFFVQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNVFDQKLMGSLCLNR
    

Molecular Weight22360.25 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.24

Net Charge (pH 7.4) -14.52

Charge Density (pH 7.0) -0.0708

GRAVY Index0.38

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index37.48

Aliphatic Index 92.19

Aromaticity 0.1542

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218467 VERIFIED: NO

Provenance & Taxonomy

OrganismSyrrhaptes paradoxus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria