Peptide Database

Peptide NameCorticotropin

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC207H309N57O57S

DescriptionStandard

        SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAQAFPLEF
    

Molecular Weight4540.08 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)1.55

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0398

GRAVY Index-0.98

Hydrophobic Moment 0.62

Boman Index-0.16

Instability Index53.68

Aliphatic Index 40.00

Aromaticity 0.1538

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1842.04

LogP -15.76

H-bond Donors 63.0

H-bond Acceptors 61.0

Rotatable Bonds 145.0

Heavy Atoms 322.0

Ring Count 12.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407767 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyCorticotropin

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermAcetylation

Other Mods13:Valine amide; 31:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

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