Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC551H882N146O168S2

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPESGIKLVIGNASLTIDMNWNIRTWIFKDSGRGTVHISKVFVTVIFSTPLDNTGPTSISFTSCQTTSGDIDIKLNGKT
    

Molecular Weight12303.90 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.22

Net Charge (pH 7.4) 0.97

Charge Density (pH 7.0) 0.0107

GRAVY Index0.05

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index19.81

Aliphatic Index 98.25

Aromaticity 0.0702

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5014.56

LogP -55.16

H-bond Donors 177.0

H-bond Acceptors 174.0

Rotatable Bonds 405.0

Heavy Atoms 867.0

Ring Count 18.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237429 VERIFIED: NO

Provenance & Taxonomy

OrganismLeucopsar rothschildi (Bali myna) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria