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MYP_148478
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Basic Information
S. litura moricin (Sl moricin; Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
42 amino acids
C208H348N60O50
Standard
Sequence
GKIPVKAIKKAGAAIGKGLRAINIASTAHDVYSFFKPKHKKK
Physicochemical Analysis
4489.36 Da
10.64
9.92
9.60
0.2363
-0.30
0.62
-0.03
12.34
86.19
0.0714
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1779.61
-14.82
62.0
62.0
156.0
318.0
7.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0321237 VERIFIED: YES
Provenance & Taxonomy
Spodoptera litura [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
28.4 μg/mL
LD50
PaperPubMed PMID: 16115804 PMID16115804 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16115804/
RECORD: Rec_0358855 VERIFIED: NO
Provenance & Taxonomy
Spodoptera litura [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0398239 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 73.8%, E 0.0%, T 9.5%, C 16.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0398682 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
Moricin
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0414818 VERIFIED: YES
Provenance & Taxonomy
Spodoptera litura [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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