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MYP_148471
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Basic Information
Syn-BNP (2S)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KSGXKHKKK
Physicochemical Analysis
0.00 Da
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0165767 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Orn, Small letters indicate D-amino acids, anticancer peptide, N-cap: HMA at 4; Orn, Small letters indicate D-amino acids, anticancer peptide, N-cap: HMA
Bio-Activity Profile
Antimicrobial Antifungal
Cryp. neoformans
2 μg/mL
MIC
PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0212058 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C14OH
None
k=D-Lys; x=D-Orn
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 28055186 PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0368622 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C14OH
None
k=D-Lys; x=D-Orn
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
>128 μg/mL
LC
PaperPubMed PMID: 28055186 PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0380913 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C14OH
None
k=D-Lys; x=D-Orn
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28055186 PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0381192 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Orn, Small letters indicate D-amino acids, anticancer peptide, N-cap: HMA at 4; Orn, Small letters indicate D-amino acids, anticancer peptide, N-cap: HMA
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
32 μg/mL
MIC
PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/