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MYP_148461
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Basic Information
I11S (Derived from tachyplesin I)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C96H148N34O21S4
Standard
Sequence
KWCFRVCYRGSCYRRCR
Physicochemical Analysis
2242.68 Da
9.93
5.72
5.45
0.3363
-0.83
0.57
-0.53
37.39
17.06
0.2353
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
940.92
-8.54
42.0
31.0
71.0
155.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0213083 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
3.13 μM
MIC
PMID26549611 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26549611/
RECORD: Rec_0239083 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 209P
3.13 μM
MIC
PMID26549611 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26549611/
RECORD: Rec_0262704 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID26549611 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26549611/
RECORD: Rec_0270932 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Tachyplesin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID26549611 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26549611/
RECORD: Rec_0358705 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
3.13 μM
MIC
PMID26549611 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26549611/
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