Peptide Database

Peptide Namep2(gag) peptide[Δ10-14,S5A]

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Enzyme modulation ▸ Enzyme inhibition ▸ Maturation inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC37H63N11O15S

DescriptionStandard

        AEAMAQVTN
    

Molecular Weight934.03 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.20

Net Charge (pH 7.4) -1.39

Charge Density (pH 7.0) -0.1335

GRAVY Index0.03

Hydrophobic Moment 0.38

Boman Index0.13

Instability Index-11.91

Aliphatic Index 65.56

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 439.83

LogP -5.87

H-bond Donors 14.0

H-bond Acceptors 15.0

Rotatable Bonds 30.0

Heavy Atoms 64.0

Ring Count 0.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329112 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Maturation inhibitor Protease inhibition

TargetCEM/LAV-1

Activity124 μM

MethodIC50

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