‹ ›
MYP_148447
← PREVIOUS NEXT → BACK
Basic Information
Mag(i+4)1, 15(K4H, A9K)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
not Standard
23 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GXGHFXHSKKKFGKAXVGEXXNS
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0078908 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 2,6,16,20; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
25 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
RECORD: Rec_0145688 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 2,6,16,20; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
3.12 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
RECORD: Rec_0154116 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 2,6,16,20; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
6.25 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
RECORD: Rec_0258591 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 2,6,16,20; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
50 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/