Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC267H441N73O86S8

DescriptionStandard

        MSVNDFKLDLVKVSKESTNSNYSVKITSYSLCTPGCKTGALMGCTMKTASCGCHVHISK
    

Molecular Weight6306.32 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.22

Charge Density (pH 7.0) 0.0614

GRAVY Index-0.04

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index35.55

Aliphatic Index 67.63

Aromaticity 0.0508

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2566.91

LogP -33.32

H-bond Donors 96.0

H-bond Acceptors 100.0

Rotatable Bonds 213.0

Heavy Atoms 434.0

Ring Count 6.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118209 VERIFIED: NO

Provenance & Taxonomy

OrganismLigilactobacillus salivarius [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria