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MYP_148427
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Basic Information
Puroindoline-A (34-46)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C98H123N23O15
Standard
Sequence
FPVTWRWWKWWKG
Physicochemical Analysis
1863.17 Da
11.17
2.76
2.55
0.2122
-0.96
0.46
0.10
58.30
22.31
0.4615
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
616.85
2.77
24.0
18.0
50.0
136.0
12.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155767 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
B. Subtilis
8 μM
IC50
PaperThe antimicrobial domains of wheat puroindolines are cell-penetrating peptides with possible intracellular mechanisms of action | PubMed PMID 27238810 PMID27238810;24098387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27238810/
RECORD: Rec_0164248 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Rhizoctonia cerealis
64
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0181025 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
mouse red blood cells
3 μg/mL
Hemolysis
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0186370 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
16 μM
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0202207 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 9027
64 μg/mL
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
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