‹ ›
MYP_148410
← PREVIOUS NEXT → BACK
Basic Information
Aureocin A53 (AucA)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
51 amino acids
C291H447N69O65S
Standard
Sequence
MSWLNFLKYIAKYGKKAVSAAWKYKGKVLEWLNVGPTLEWVWQKLKKIAGL
Physicochemical Analysis
5984.15 Da
10.07
7.49
7.25
0.1469
-0.08
0.72
0.14
-3.89
101.37
0.1765
31970.00
31970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2173.93
-6.33
77.0
74.0
199.0
426.0
15.0
53.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0010536 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus aureus A53 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 29213
128 μM
MIC
PMID26771761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26771761/
RECORD: Rec_0012645 VERIFIED: NO
Provenance & Taxonomy
Staphylococcus aureus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2023/0416797 A1 Evidence URLhttps://patents.google.com/patent/US20230416797A1/en PatentUS 2023/0416797 A1
RECORD: Rec_0024659 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus aureus [Bacterium]
Bacteriocin
1280
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Formylation
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus (MRSA)
PMID12054867 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054867/
RECORD: Rec_0034015 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus aureus [Bacterium]
Bacteriocin
1280
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Formylation
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PMID12054867 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054867/
RECORD: Rec_0049740 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus aureus [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
The N-terminus of the peptide is formylated. leaderless. SAR: Removal of the N-terminal Met had no effect on peptide activity
Bio-Activity Profile
Antimicrobial
food-related Listeria monocytogenes, S. simulans 22, Staphylococcus aureus (MRSA)
PaperBiochemical characterisation and genetic analysis of aureocin A53, a new, atypical bacteriocin from Staphylococcus aureus.
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4