Peptide Database

Peptide NameGranulosusin-E1 antimicrobial peptide (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC335H563N87O105S6

DescriptionStandard

        MFTMKKSLLVLFFLGIVSLSLCEEERNADEDDGEMTEEVKRGILDTLKQLGKAAAQSLLSKAACKLAKTC
    

Molecular Weight7681.96 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0216

GRAVY Index0.05

Hydrophobic Moment 0.71

Boman Index0.03

Instability Index40.68

Aliphatic Index 100.43

Aromaticity 0.0429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3124.82

LogP -28.69

H-bond Donors 111.0

H-bond Acceptors 110.0

Rotatable Bonds 274.0

Heavy Atoms 533.0

Ring Count 3.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247392 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops granulosus [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0326498 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops granulosus [Animal]

Tax ID325557

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal