Peptide Database

Peptide NameMedusin-DA1 (MDS-DA1) (Medusin-PD) (Phyllin-PD)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC341H564N90O112S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSVCEEEKRENEEEKNEQEEDDREERNEEKRLLGMIPLAISAISSLSKLG
    

Molecular Weight7812.86 Da

Isoelectric Point (pI)4.64

Net Charge (pH 7.0)-6.47

Net Charge (pH 7.4) -6.74

Charge Density (pH 7.0) -0.0952

GRAVY Index-0.41

Hydrophobic Moment 0.51

Boman Index-0.10

Instability Index63.93

Aliphatic Index 103.24

Aromaticity 0.0441

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3318.72

LogP -29.11

H-bond Donors 114.0

H-bond Acceptors 109.0

Rotatable Bonds 282.0

Heavy Atoms 546.0

Ring Count 4.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0253943 VERIFIED: YES

Provenance & Taxonomy

OrganismAgalychnis dacnicolor [Animal]

FamilyFrog skin active peptide (FSAP); Medusin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-positive Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0260097 VERIFIED: YES