Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length185 amino acids

Chemical FormulaC923H1471N255O250S7

DescriptionStandard

        PTPPPMAHEPTLLLAVTEFVANSAAFTYFTAGALRRNISSDMIPRRFPLQLRTKSMGVFSPQLQELYPDQPMELHLWARQQPLLSCHPDALHGTLLSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELHGLSVPQVKRLETLLKFALWLFGVPRANSKCCPRAVP
    

Molecular Weight20364.57 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)6.38

Net Charge (pH 7.4) 6.00

Charge Density (pH 7.0) 0.0345

GRAVY Index0.03

Hydrophobic Moment 0.59

Boman Index0.09

Instability Index53.50

Aliphatic Index 97.03

Aromaticity 0.0703

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7914.55

LogP -91.47

H-bond Donors 272.0

H-bond Acceptors 268.0

Rotatable Bonds 639.0

Heavy Atoms 1435.0

Ring Count 41.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071214 VERIFIED: NO

Provenance & Taxonomy

OrganismSetophaga kirtlandii (Kirtland`s warbler) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria