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MYP_148283
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Basic Information
Sub3-DAgp
Antimicrobial
Antimicrobial ▸ Antibacterial
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
AXXWXIVVIXVXXH
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0049335 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Sub3
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
X= α-amino-3-guanidino-propionic acid, D-Ala at 1st position, D-His at 14th position
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
1 μg/mL
MIC
Mouse serum: Half-life >480 min
PaperKnappe D, Henklein P, Hoffmann R, Hilpert K. Easy strategy to protect antimicrobial peptides from fast degradation in serum. Antimicrob Agents Chemother. 2010 Sep;54(9):4003-5. PMID:20585128 https://pubmed.ncbi.nlm.nih.gov/20585128/ PMID20585128 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20585128/
RECORD: Rec_0402048 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Sub3
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
X= α-amino-3-guanidino-propionic acid, D-Ala at 1st position, D-His at 14th position
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
2 μg/mL
MIC
Mouse serum: Half-life >480 min
PaperKnappe D, Henklein P, Hoffmann R, Hilpert K. Easy strategy to protect antimicrobial peptides from fast degradation in serum. Antimicrob Agents Chemother. 2010 Sep;54(9):4003-5. PMID:20585128 https://pubmed.ncbi.nlm.nih.gov/20585128/ PMID20585128 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20585128/