Peptide Database

Peptide NameEC-hepcidin2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC148H241N31O38S2

DescriptionStandard

        MKVFSIAVAVTLVLAFICILESSAVPFTGV
    

Molecular Weight3126.81 Da

Isoelectric Point (pI)5.75

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0169

GRAVY Index1.90

Hydrophobic Moment 0.28

Boman Index0.62

Instability Index33.28

Aliphatic Index 149.33

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1062.90

LogP -4.97

H-bond Donors 38.0

H-bond Acceptors 40.0

Rotatable Bonds 98.0

Heavy Atoms 219.0

Ring Count 4.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392950 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)