Peptide Database

Peptide NameBeta-defensin 34 (BD-34) (mBD-34) (Defensin; beta 34)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC409H627N115O112S10

DescriptionStandard

        MKTFLFLFAVLFFWSQPRMHFFFFDEKCSRINGRCTASCLKNEELVALCWKNLKCCVTVQSCGRSKGNQSDEGSGHMGTRG
    

Molecular Weight9267.71 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)4.61

Net Charge (pH 7.4) 4.18

Charge Density (pH 7.0) 0.0569

GRAVY Index-0.13

Hydrophobic Moment 0.50

Boman Index0.00

Instability Index51.54

Aliphatic Index 56.54

Aromaticity 0.1358

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3685.05

LogP -37.24

H-bond Donors 137.0

H-bond Acceptors 129.0

Rotatable Bonds 310.0

Heavy Atoms 646.0

Ring Count 16.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101476 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic