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MYP_148164
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Basic Information
Brevinin-1RE1
Antimicrobial
Antimicrobial ▸ Antifungal
Standard
25 amino acids
C123H203N29O31S3
Standard
Sequence
FLPGLECVSGLKIVPTVFCAITRIC
Physicochemical Analysis
2680.30 Da
7.96
0.73
0.48
0.0293
1.37
0.59
0.42
29.38
132.40
0.0800
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
930.05
-5.14
35.0
35.0
83.0
186.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0355772 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. parapsilosis ATCC 22019
5 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0378756 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028
2.5 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0378821 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Enterococcus faecalis ATCC 29212
10 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0386506 VERIFIED: YES
Provenance & Taxonomy
Rana exilispinosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 25923
10 μg/mL
MIC
PaperNovel peptides from skins of amphibians showed broad-spectrum antimicrobial activities.
RECORD: Rec_0386781 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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