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MYP_148155
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Basic Information
T9I (Derived from RI16)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C99H187N39O17
Standard
Sequence
RFRRLRKKIRKRLKKI
Physicochemical Analysis
2195.80 Da
12.00
10.76
10.54
0.6722
-1.69
0.77
-1.04
61.67
97.50
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1001.32
-6.68
40.0
28.0
85.0
155.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126590 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa LC
64 μM
MIC
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0146548 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
macrophage cells is larger than 256 μM
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0155864 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 29213
256 μM
MIC
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0166022 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Murine macrophage cells RAW 264.7[50% Cell death >256 microM]
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
RECORD: Rec_0203928 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID25494332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25494332/
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