Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC406H657N123O110S11

DescriptionStandard

        MALSSQIWAACLLLLLLLASLTSGSVFPQQTGQLAELQPQDRAGARAGWTPMLQRRRRRDTHFPIYIFCCGCCHRSKCGMCCKT
    

Molecular Weight9374.03 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)6.60

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0785

GRAVY Index0.08

Hydrophobic Moment 0.52

Boman Index0.02

Instability Index74.71

Aliphatic Index 82.62

Aromaticity 0.0714

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3735.93

LogP -38.40

H-bond Donors 141.0

H-bond Acceptors 130.0

Rotatable Bonds 306.0

Heavy Atoms 650.0

Ring Count 14.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186975 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyHepcidin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0224395 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyHepcidin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetN. cinerea

RECORD: Rec_0286170 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyHepcidin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus epidermidis

RECORD: Rec_0393372 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyHepcidin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli