Peptide Database

Peptide NameEsculentin-1-OA1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC222H374N60O55S3

DescriptionStandard

        GLFSKFVGKGIKNFLIKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC
    

Molecular Weight4859.91 Da

Isoelectric Point (pI)9.84

Net Charge (pH 7.0)5.82

Net Charge (pH 7.4) 5.53

Charge Density (pH 7.0) 0.1266

GRAVY Index0.52

Hydrophobic Moment 0.71

Boman Index0.20

Instability Index-10.40

Aliphatic Index 114.13

Aromaticity 0.0652

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1846.78

LogP -12.84

H-bond Donors 66.0

H-bond Acceptors 65.0

Rotatable Bonds 173.0

Heavy Atoms 340.0

Ring Count 4.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403869 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana andersonii [Animal]

FamilyEsculentin

Structure & Mods

ConfigLinear peptide with a single intramolecular disulfide-stabilized loop [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Disulfide40-46

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

Activity0.25 μM

MethodMIC

RECORD: Rec_0423386 VERIFIED: YES