Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC420H669N123O126S13

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAIPFAGVQEPEEAGSNDTPVVAHQEMSAESSMMSNHIRQKRQSHLSLCRWCCNCCRSNKGCGFCCRF
    

Molecular Weight9874.40 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.15

Hydrophobic Moment 0.66

Boman Index0.07

Instability Index72.69

Aliphatic Index 72.67

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3985.05

LogP -46.01

H-bond Donors 147.0

H-bond Acceptors 143.0

Rotatable Bonds 326.0

Heavy Atoms 682.0

Ring Count 13.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110476 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis aureus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal

RECORD: Rec_0170601 VERIFIED: NO