Peptide Database

Peptide NameBrevinin-2KK2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC376H625N97O115S5

DescriptionStandard

        MFTTKKPMLLLFFLGTISLSLCQEEERGADEDEVIEEEVKRGIFSVVKGVLKAAGKNVAKNVAGSLLDQLKCKISGEC
    

Molecular Weight8504.89 Da

Isoelectric Point (pI)5.41

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0194

GRAVY Index0.08

Hydrophobic Moment 0.67

Boman Index0.06

Instability Index30.40

Aliphatic Index 102.44

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3435.01

LogP -30.46

H-bond Donors 120.0

H-bond Acceptors 119.0

Rotatable Bonds 301.0

Heavy Atoms 593.0

Ring Count 5.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329237 VERIFIED: NO

Provenance & Taxonomy

OrganismRana kukunoris [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence