Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length155 amino acids

Chemical FormulaC804H1263N207O231S4

DescriptionStandard

        MMLKSCALGFQQSRLILNRYELWEDDATSPTLIWSLAGELSRHNIDNYAQQNSAVNTKVAVLDPKIATQTPGLSIPDAKVHGPTVLGTPTPEEKDFRDDILIFPISNIPAIYVYLSKIEELDSDKYTRRQLDRKFKHAKDFGIVIYLWFLMLGLI
    

Molecular Weight17653.14 Da

Isoelectric Point (pI)5.89

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.66

Charge Density (pH 7.0) -0.0144

GRAVY Index-0.15

Hydrophobic Moment 0.72

Boman Index0.06

Instability Index43.66

Aliphatic Index 102.58

Aromaticity 0.0968

Extinction Coeff. Reduced 25440.00

Extinction Coeff. Oxidized 25440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7024.05

LogP -56.17

H-bond Donors 241.0

H-bond Acceptors 236.0

Rotatable Bonds 581.0

Heavy Atoms 1246.0

Ring Count 30.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338021 VERIFIED: YES

Provenance & Taxonomy

OrganismXenorhabdus beddingii [Bacterium]

Tax ID40578

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)