Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length385 amino acids

Chemical FormulaC1917H2997N523O540S17

DescriptionStandard

        MRIRRFLLRNSNLSLHSGQGVRASLSNNYVSVSGNWKVFFITLYGTFDLSVDGTSISISLNLGKDQSGRPTASMTHCSNSTGHVSIEISGHLRVNYLAETGAPQSPVMLRPSIPFYFPIQLHTSSFRAIIPQLARLYPNMELEFETSPQSAPFLMFTPGNVTLMPVMDIQAFALLPNSSGHKPLFQLRAVSLNLARAIKGHVCHGWKPLAQLKDWETMQLIDSGGYLFLERGKLSPPGKRKWTQVEQLTIIDGTGFTGPPNPITWFNPTPRTNISITINVNSSRIVGSLTTVSELKLELKHSNIGFFNVSCFPSAFLECPLQAGLHGKKLHGRVPGEATWSQIKTHCSLAGNGIPCLKMNLMESIHNYYALHIIYPSLDGKNSCY
    

Molecular Weight42555.59 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)12.67

Net Charge (pH 7.4) 11.58

Charge Density (pH 7.0) 0.0329

GRAVY Index-0.07

Hydrophobic Moment 0.69

Boman Index0.11

Instability Index40.50

Aliphatic Index 89.14

Aromaticity 0.0909

Extinction Coeff. Reduced 47900.00

Extinction Coeff. Oxidized 48275.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101283 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera physalus (Fin whale) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria