Peptide Database

Peptide Name[Asp8,Ala15]Cyclo(Asp8-Lys12)(Lys21-Asp25)GRF(1-29)-NH2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC148H227N37O42S5

DescriptionStandard

        YADAIFTCYCLDSYRCYCLKVLAQLSARC
    

Molecular Weight3356.93 Da

Isoelectric Point (pI)7.80

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.42

Charge Density (pH 7.0) 0.0244

GRAVY Index0.53

Hydrophobic Moment 0.48

Boman Index0.11

Instability Index23.13

Aliphatic Index 91.03

Aromaticity 0.1724

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1287.24

LogP -10.14

H-bond Donors 52.0

H-bond Acceptors 48.0

Rotatable Bonds 105.0

Heavy Atoms 232.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044590 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyGHRH/CRF

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsComposite modified token cyclo

Bio-Activity Profile

Function

Endocrine

MethodHPLC

Half-LifePorcine plasma, in vitro; >14400 s