Peptide Database

Peptide NameDELTA-limacoditoxin(2)-Dv11 (DELTA-LCTX(2)-Dv11) (Cecropin-like peptide) (Vulnericin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Insecticidal/Pest control ▸ Insecticidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC284H473N75O72S2

DescriptionStandard

        MKFAKTFLLLFVVLLLLSIVMAEPKRGFGKLLRKVFKVGRRVAGSAAEISGSSGGEE
    

Molecular Weight6154.38 Da

Isoelectric Point (pI)10.62

Net Charge (pH 7.0)5.51

Net Charge (pH 7.4) 5.28

Charge Density (pH 7.0) 0.0967

GRAVY Index0.54

Hydrophobic Moment 0.99

Boman Index0.17

Instability Index36.94

Aliphatic Index 114.56

Aromaticity 0.0877

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2358.43

LogP -16.64

H-bond Donors 85.0

H-bond Acceptors 80.0

Rotatable Bonds 214.0

Heavy Atoms 433.0

Ring Count 6.0

Amide Bonds 56.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0108723 VERIFIED: YES

Provenance & Taxonomy

OrganismDoratifera vulnerans [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Anti-Gram-positive Toxin Insecticidal Non-hemolytic

TargetAcinetobacter baumannii

RECORD: Rec_0176583 VERIFIED: YES

Provenance & Taxonomy

OrganismDoratifera vulnerans [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Anti-Gram-positive Toxin Insecticidal Non-hemolytic

TargetHaemonchus contortus

RECORD: Rec_0284475 VERIFIED: YES

Provenance & Taxonomy

OrganismDoratifera vulnerans [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Anti-Gram-positive Toxin Insecticidal Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0364016 VERIFIED: YES

Provenance & Taxonomy

OrganismDoratifera vulnerans [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Anti-Gram-positive Toxin Insecticidal Non-hemolytic

TargetD. melanogaster